Kentucky Lake Section

Serving Chemists in Southern Illinois, Western Kentucky, and Northwestern Tennessee

September Meeting

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Thursday September 21, 2017 6:00 PM - 8:00 PM
1050 Union University Drive, Jackson, TN  (map)

Union University

Dinner @ 6

Choice of Chicken Marsala or Herb Crusted Tilapia, salad, garlic mashed potatoes, mixed vegetables, and pie dessert bar

The price is $10 (Students $5)

Presentation @ 7

Speaker: Dr. John Hershberger, Assistant Professor of Chemistry at Arkansas State University

Title: Making Old Reactions New Again:  A Tale in Two Parts

Abstract: This talk focuses on two tales of new reaction sequence development using undergraduate researchers. The first involves development of a fluoride-free cross-coupling of arylsilicon and arylboron derivatives. Cross-coupling has led to great advances in the synthesis of biaryl compounds, which can be found in everything from pharmaceuticals to advanced materials. The new reaction removes the need for the halide, using oxygen as the terminal oxidant. The second involves new modifications of Biginelli adducts. The Biginelli reaction is over 100 years old and gives rise to the dihydropyrimidinone, which is itself a privileged structure as well as a precursor to other bioactive molecules. We are taking the easily accessible Biginelli products and generating new derivatives using simple, robust reactions. 

Bio: John is originally from the Kansas City area. He received his undergraduate degree from the Missouri University of Science and Technology (formerly the University of Missouri-Rolla). He then earned his Ph.D., at the University of Kansas, followed by postdoctoral work at both The University of Michigan and The University of Wisconsin. After a visiting year as an Assistant Professor at Hamilton College in upstate New York, he is currently an Assistant Professor of Chemistry at Arkansas State University where his research interests are in new reaction development and the discovery of new bioactive compounds.

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